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The team of Professor Peng Longkai of Central South University put forward the original new style

The team of Professor Peng Longkai of Central South University put forward the original new style,Increase the rate of "extremely low weight" for kidney utilization
Source: the number of hits in Xiangya No.2 Hospital: 1708 release time: 2018, 03 month 22, author: Yuan Xuan

The shortage of transplanted organs has always been a global problem. However, the organs donated by caring people often cannot be used because of limited conditions, and very low birth weight kidneys are one of them.

To solve this problem, Professor Peng Longkai, director of the Department of organ transplantation, Xiangya No.2 Hospital of Central South University, has made breakthrough progress after years of exploration, bringing new hope for the transplant treatment of uremic patients. The day before, Professor Peng Longkai team related results in the "American Journal of organ transplantation" (AJT).

Peng Longkai introduced, compared with adult organ donor, the source of organ donor in children is relatively sufficient. However, the success rate of these organs is much lower than that of adult donors. This is related to the small size of the organs, the difficulty of operation, the difficulty of postoperative management and the incidence of various complications. Among them, the most perplexing clinicians are "graft embolism" and "high perfusion injury" after transplantation. The former may lead to the failure of the operation, which affects the short-term survival of the graft. The latter may lead to the proliferation of mesangial cells and glomerulosclerosis, which may affect the long-term survival of the transplanted kidney.
Although the team had completed more than 200 children's kidney transplantation, the global problem of kidney transplantation for very young and very low birth weight infants younger than 5 month old and weighing less than 5 kg is still puzzled. "Only sporadic reports at home and abroad, in the case of prophylactic use of anticoagulant drugs, renal embolism rate is still as high as 60% - 80%." Peng Long said.  However, this problem is solved by team creatively put forward the new method of "double kidney whole transplantation" using the distal aorta to establish the outflow tract. By using the new method, the team has completed 12 cases of very low birth weight and very low birth weight kidneys transplantation without the use of anticoagulant drugs. There is no case of embolism in the 3.5 cases. "According to the literature search, this is the world's most successful minimum weight newborn donor kidney transplantation." Team members and chief physician Yu Shaojie said.

In this article entitled (A novel technique for en bloc kidney transplantation from infant donors with extremely low body weight by using the distal abdominal aorta as an outflow tract) the original clinical team in the article, this experience will be introduced to the world.